Untitled Document
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Sarah L. Kieweg
Assistant Professor (Ph.D., Duke University)
785-864-3354
kieweg@ku.edu
Biofluids, Drug Delivery, Transport Phenomena |
Career History
- Assistant Professor, Mechanical Engineering, The University of Kansas
- Post-doctoral Research Associate, Biomedical Engineering, Duke University, 2005
Education
- Ph.D. Biomedical Engineering, Duke University, 2005
- Certificate in Biomolecular and Tissue Engineering, Duke University, 2005
- M.S. Bioengineering, University of California, San Diego 1999
- B.S.E. Biomedical Engineering, Duke University, 1997
Professional Organizations
- American Society of Mechanical Engineers (ASME)
- Biomedical Engineering Society (BMES)
Honors and Awards
- National Science Foundation Graduate Research Fellow (1997-2000)
- NIH Biomolecular and Tissue Engineering Fellow (2000-2002)
- Science and Technology Policy Graduate Fellow, The National Academies (2003)
Teaching Interests
- Fluid Mechanics (ME 510: Spring 2006)
- Computational Methods
- Biofluids (ME 790: Fall 2006)
- Drug Delivery and Transport Phenomena
Research Interests
- Drug delivery of microbicides to the lower female reproductive tract for the prevention of HIV transmission
- Non-Newtonian fluid mechanics
- Squeezing flows and gravity-driven flows
- Rheology
- Transport phenomena
Publications
- S.L. Kieweg and D.F. Katz. Interpreting properties of microbicide drug delivery gels: Analyzing deployment due to squeezing. Submitted.
- S.L. Kieweg and D.F. Katz. Squeezing flows of microbicidal gel formulations for vaginal drug delivery. Journal of Biomechanical Engineering, accepted, 2006.
- S.L. Kieweg, A.R. Geonnotti, D.F. Katz. Gravity-induced coating flows of vaginal gel formulations: in vitro experimental analysis. Journal of Pharmaceutical Sciences 93(12): 2941-2952, December 2004.
- S. Driscoll (Kieweg), M. Hawkins, F. Balis, W. Pfleiderer, and W. Laws. Fluorescence properties of a new guanosine analog incorporated into small oligonucleotides. Biophysical Journal 73: 3277-3286, December 1997.
Presentations
- S.L. Kieweg, A.R. Geonnotti, and D.F. Katz. Determinants of vaginal coating by anti-HIV and other drug delivery formulations. Biomedical Engineering Society (BMES) meeting, Baltimore, MD, September, 2005.
- S.L. Kieweg and D.F. Katz. Mechanisms of vaginal/rectal coating by microbicidal formulations: macro-scale processes. Microbicides 2002 meeting in Antwerp, Belgium, 2002.
- S.L. Driscoll (Kieweg) and D.F. Katz. Posture influences vaginal gel distributions in women: theoretical models and in vitro simulations of gravitational flows. Meeting of the American Society of Reproductive Medicine, Fertility and Sterility, 76(3): O47, 2001.
Posters
- D.H. Owen, S.L. Kieweg, A.L. Zimmerman, and D.F. Katz. Yield stress analyses of vaginal contraceptive and microbicidal drug delivery gels. Annual meeting of the American Association of Pharmaceutical Sciences, Nashville, Tennessee, November, 2005.
- A.R. Geonnotti, S.L. Kieweg, and D.F. Katz. Distribution and erosion of microbicide formulation coating: mechanistic analysis. Alliance for Microbicide Development meeting, Washington, DC, 2005.
- S.L. Kieweg and D.F. Katz. Effects of squeezing flows on distribution and retention of microbicide formulations: experimental simulations and mathematical models. Microbicides
2004 meeting in London, England, 2004.
- D.H. Owen, A.R. Geonnotti, S.L. Kieweg, R. Schnaare, and D.F. Katz. Mechanistic analysis of deployment of prototype formulations for delivery of topical anti-HIV agents to the female reproductive tract. Annual meeting of the American Association of Pharmaceutical Sciences, Baltimore, Maryland, 2004.
- S.L. Kieweg, T.P. Witelski, and D.F. Katz. Epithelial coating mechanisms by anti-HIV vaginal drug delivery formulations: gravitational effects. Biomedical Engineering Society meeting in
Nashville, Tennessee, 2003.
- S.L. Driscoll (Kieweg) and D.F. Katz. Effects of gravity on flow of vaginal gel formulations: in vitro studies. Third NIAID Topical Microbicides Pre-clinical Workshop in Baltimore, Maryland, 2001.
